Home > INFERTILITY TREATMENT > Infertility-Diagnosis > PGD
PGD is a form of genetic diagnosis performed prior to implantation, so this is an
adjunct to assisted reproductive technology, and always performed following an in
vitro fertilization (IVF) cycle to obtain oocytes or fertilized embryos. In briefly,
the procedure of PGD is consisted of the biopsy of one or two blastomeres from 4-
to 8-cells-embryos and identification of a specific genetic defect using a fluorescent
in situ hybridization (FISH) technique for chromosome adnormalities and mutation
detection methods for a single gene disorder.
- Couples at risk for transmitting a specific genetic disease or abnormality to their
offspring
- Carriers of AD and AR disorders
- Female carriers of X-linked disorders
- Carriers of balanced chromosome rearrangements (translocation and inversion)
- Some women having had multiple miscarriage
- Failed previous attempts at embryo transfer following IVF